› 4pzl

X-ray diffraction
2.1Å resolution

The crystal structure of adenylate kinase from Francisella tularensis subsp. tularensis SCHU S4

Released:
DOI: 10.2210/pdb4pzl/pdb
PDB entry 4pzl coloured by chain, front view.
PDB entry 4pzl coloured by chain, side view.
PDB entry 4pzl coloured by chain, top view.
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Entry authors: Tan K, Zhou M, Kwon K, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
ATP + AMP = 2 ADP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177670 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate kinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 242 amino acids
Theoretical weight: 27.28 KDa
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5NFR4 (Residues: 1-218; Coverage: 100%)
Gene names: FTT_1161, adk
Sequence domains:
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

4 bound ligands:
Ligand CA 2 x CA
Ligand FMT 4 x FMT
Ligand GOL 2 x GOL
Ligand PEG 1 x PEG
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P32
Unit cell:
a: 65.022Å b: 65.022Å c: 214.732Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.191 0.237
Expression system: Escherichia coli

Quick links