X-ray diffraction
1.45Å resolution

Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique Zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication


Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Initiator protein NS1 Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 32.34 KDa
Source organism: Murine minute virus strain MVM prototype
Expression system: Escherichia coli
  • Canonical: P03134 (Residues: 1-255; Coverage: 38%)
Gene name: NS1
Sequence domains: Parvovirus non-structural protein 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21212
Unit cell:
a: 56.94Å b: 121.65Å c: 41.82Å
α: 90° β: 90° γ: 90°
R R work R free
0.167 0.166 0.185
Expression system: Escherichia coli