› 4peg

X-ray diffraction
2Å resolution

Dbr1 in complex with guanosine-5'-monophosphate

Released:
DOI: 10.2210/pdb4peg/pdb
PDB 4peg coloured by chain and viewed from the front.
PDB 4peg coloured by chain and viewed from the side.
PDB 4peg coloured by chain and viewed from the top.
Source organism: Entamoeba histolytica
Entry authors: Montemayor EJ, Katolik A, Clark NE, Taylor AB, Schuermann JP, Combs DJ, Johnsson R, Holloway SP, Stevens SW, Damha MJ, Hart PJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallophos domain-containing protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 360 amino acids
Theoretical weight: 41.91 KDa
Source organism: Entamoeba histolytica
Expression system: Escherichia coli
UniProt:
  • Canonical: C4M1P9 (Residues: 1-354; Coverage: 100%)
Gene name: EHI_062730
Sequence domains: Calcineurin-like phosphoesterase

Ligands and Environments

4 bound ligands:
Ligand MN 5 x MN
Ligand 5GP 5 x 5GP
Ligand SO4 5 x SO4
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 72.831Å b: 141.499Å c: 212.942Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.229
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease.
Gounder et al. (2019)
5 more

4 mentions without citation

Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.
Montemayor et al. (2014)
3 more