4pas

X-ray diffraction
1.62Å resolution

Heterodimeric coiled-coil structure of human GABA(B) receptor

Released:
Source organism: Homo sapiens
Primary publication:
Heterodimeric coiled-coil interactions of human GABAB receptor.
Proc Natl Acad Sci U S A 111 6958-63 (2014)
PMID: 24778228

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-131164 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Gamma-aminobutyric acid type B receptor subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 41 amino acids
Theoretical weight: 5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UBS5 (Residues: 879-919; Coverage: 4%)
Gene names: GABBR1, GPRC3A
Gamma-aminobutyric acid type B receptor subunit 2 Chain: B
Molecule details ›
Chain: B
Length: 41 amino acids
Theoretical weight: 4.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75899 (Residues: 779-819; Coverage: 5%)
Gene names: GABBR2, GPR51, GPRC3B
Sequence domains: Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2221
Unit cell:
a: 46.721Å b: 54.654Å c: 55.347Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.217
Expression system: Escherichia coli