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Complex of Voltage-gated ion channel in a the presence of channel blocking compound

X-ray diffraction
2.89Å resolution
PDB entry 4p9o coloured by chain, front view.
PDB entry 4p9o coloured by chain, side view.
PDB entry 4p9o coloured by chain, top view.
Source organism: Magnetococcus marinus MC-1
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1
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Assembly Name: Ion transport domain-containing protein
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Multimeric state: homo tetramer
Accessible surface area: 16697.69 Å2
Buried surface area: 7321.39 Å2
Dissociation area: 3,385.99 Å2
Dissociation energy (ΔGdiss): 28.74 kcal/mol
Dissociation entropy (TΔSdiss): 34.82 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-106115
Assembly 2 (preferred)
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Assembly Name: Ion transport domain-containing protein
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Multimeric state: homo tetramer
Accessible surface area: 17050.5 Å2
Buried surface area: 7029.88 Å2
Dissociation area: 3,254.14 Å2
Dissociation energy (ΔGdiss): 23.76 kcal/mol
Dissociation entropy (TΔSdiss): 34.62 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-106115

Macromolecules

Ion transport domain-containing protein
Chains: A, B, C, D
Length: 149 amino acids
Theoretical weight: 16.84 KDa
Source organism: Magnetococcus marinus MC-1
Expression system: Escherichia coli
UniProt:
  • Canonical: A0L5S6 (Residues: 130-274; Coverage: 53%)
Gene name: Mmc1_0798
Pfam: Ion transport protein
InterPro:
CATH: Helix Hairpins
Ion transport domain-containing protein in PDB entry 4p9o, assembly 2, front view.
Ion transport domain-containing protein in PDB entry 4p9o, assembly 2, side view.
Ion transport domain-containing protein in PDB entry 4p9o, assembly 2, top view.
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