› 4p0o

X-ray diffraction
1.8Å resolution

Cleaved Serpin 42Da

Released:
DOI: 10.2210/pdb4p0o/pdb
PDB entry 4p0o coloured by chain, front view.
PDB entry 4p0o coloured by chain, side view.
PDB entry 4p0o coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster.
Ellisdon AM, Zhang Q, Henstridge MA, Johnson TK, Warr CG, Law RH, Whisstock JC
BMC Struct Biol 14 14 (2014)
PMID: 24758516

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181582 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 393 amino acids
Theoretical weight: 44.31 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7K8Y5 (Residues: 33-424; Coverage: 99%)
Gene names: CG9453, Dmel\CG9453, Dmel_CG9453, Serp2, Sp4, Spn4, Spn42Da, Spn4A, dSerp2, sp4, spn4
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: I222
Unit cell:
a: 87.22Å b: 109.77Å c: 140.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.185
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Neonatal Hypoxia Ischaemia: Mechanisms, Models, and Therapeutic Challenges.
Millar et al. (2017)
7 other articles

2 mentions without citation

Serpins in arthropod biology.
Meekins et al. (2017)
1 more