4oya

X-ray diffraction
2.03Å resolution

Human solAC Complexed with (4-Aminofurazan-3-yl)-[3-(1H-benzoimidazol-2-ylmethoxy)phenyl]methanone

Released:

Function and Biology Details

Reaction catalysed:
ATP = 3',5'-cyclic AMP + diphosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate cyclase type 10 Chain: A
Molecule details ›
Chain: A
Length: 470 amino acids
Theoretical weight: 53.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q96PN6 (Residues: 1-469; Coverage: 29%)
Gene names: ADCY10, SAC
Sequence domains: Adenylate and Guanylate cyclase catalytic domain
Structure domains: Nucleotide cyclase

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P63
Unit cell:
a: 99.669Å b: 99.669Å c: 98.175Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.161 0.21
Expression system: Spodoptera frugiperda