› 4oxx

X-ray diffraction
1.21Å resolution

Crystal Structure of Cindoxin, Surface Entropy reduction Mutant

Released:
DOI: 10.2210/pdb4oxx/pdb
PDB entry 4oxx coloured by chain, front view.
PDB entry 4oxx coloured by chain, side view.
PDB entry 4oxx coloured by chain, top view.
Source organism: Citrobacter braakii
Primary publication:
Crystal structure of cindoxin, the P450cin redox partner.
Madrona Y, Hollingsworth SA, Tripathi S, Fields JB, Rwigema JC, Tobias DJ, Poulos TL
Biochemistry 53 1435-46 (2014)
PMID: 24533927

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186614 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cindoxin Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 16.87 KDa
Source organism: Citrobacter braakii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8VQF4 (Residues: 1-154; Coverage: 100%)
Gene name: cinC
Sequence domains: Flavodoxin
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand FMN 1 x FMN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P3221
Unit cell:
a: 82.109Å b: 82.109Å c: 37.042Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.142 0.141 0.16
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Updating the Paradigm: Redox Partner Binding and Conformational Dynamics in Cytochromes P450.
Poulos et al. (2022)
1 more

1 mention without citation

Evolutionary Relationships Between Low Potential Ferredoxin and Flavodoxin Electron Carriers.
Campbell et al. (2019)