4oxb

X-ray diffraction
1.5Å resolution

Structure of ECP with sulphate anions at 1.50 Angstroms

Released:
Source organism: Homo sapiens
Entry authors: Blanco JA, Boix E, Moussaoui M

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eosinophil cationic protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 134 amino acids
Theoretical weight: 15.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12724 (Residues: 28-160; Coverage: 100%)
Gene names: ECP, RNASE3, RNS3
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: C2
Unit cell:
a: 92.73Å b: 51.286Å c: 55.619Å
α: 90° β: 111.25° γ: 90°
R-values:
R R work R free
0.182 0.179 0.232
Expression system: Escherichia coli BL21(DE3)