Structure analysis

crystal structure of the C-terminal domain of p100/NF-kB2

X-ray diffraction
3.35Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: homo dimer
Accessible surface area: 28600 Å2
Buried surface area: 3800 Å2
Dissociation area: 1,500 Å2
Dissociation energy (ΔGdiss): 18 kcal/mol
Dissociation entropy (TΔSdiss): 14 kcal/mol
Interface energy (ΔGint): -77 kcal/mol
Symmetry number: 2
Assembly 2
Download    3D Visualisation
Multimeric state: homo dimer
Accessible surface area: 30400 Å2
Buried surface area: 2000 Å2
Dissociation area: 650 Å2
Dissociation energy (ΔGdiss): 4 kcal/mol
Dissociation entropy (TΔSdiss): 14 kcal/mol
Interface energy (ΔGint): -60 kcal/mol
Symmetry number: 2

Macromolecules

Chain: A
Length: 359 amino acids
Theoretical weight: 38.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00653 (Residues: 407-765; Coverage: 40%)
Gene names: LYT10, NFKB2
Pfam: Ankyrin repeat
InterPro:

Search similar proteins