4ool

X-ray diffraction
2.3Å resolution

Crystal structure of PBP3 in complex with compound 14 ((2E)-2-({[(2S)-2-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1,5-dihydroxy-4-oxo-1,4-dihydropyridin-2-yl)methoxy]imino}acetyl]amino}-3-oxopropyl]oxy}imino)pentanedioic acid)

Released:
Source organism: Pseudomonas aeruginosa PA1R
Entry authors: Han S, Caspers N, Knafels JD

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell division protein FtsI [Peptidoglycan synthetase] Chain: A
Molecule details ›
Chain: A
Length: 538 amino acids
Theoretical weight: 58.33 KDa
Source organism: Pseudomonas aeruginosa PA1R
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 68.28Å b: 83.54Å c: 89.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.186 0.241
Expression system: Escherichia coli