› 4olr

X-ray diffraction
1.1Å resolution

[Leu-5]-Enkephalin mutant - YVVFV

Released:
DOI: 10.2210/pdb4olr/pdb
PDB 4olr coloured by chain and viewed from the front.
PDB 4olr coloured by chain and viewed from the side.
PDB 4olr coloured by chain and viewed from the top.
Source organism: synthetic construct
Entry authors: Sangwan S, Eisenberg D, Sawaya MR, Do TD, Bowers MT, Lapointe NE, Teplow DB, Feinstein SC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
[Leu-5]-Enkephalin mutant - YVVFV Chains: A, B
Molecule details ›
Chains: A, B
Length: 5 amino acids
Theoretical weight: 626 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MPD 1 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 9.75Å b: 21.38Å c: 19.05Å
α: 90° β: 93.17° γ: 90°
R-values:
R R work R free
0.153 0.15 0.187
Expression system: Not provided

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Citations

4 review citations

Recent advances in mass spectrometry analysis of neuropeptides.
Phetsanthad et al. (2021)
3 more

1 mention without citation

Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicity.
Do et al. (2014)