› › Structure analysis

Crystal structure of W741L-AR-LBD bound with co-regulator peptide

X-ray diffraction
2.8Å resolution
PDB entry 4olm coloured by chain, front view.
PDB entry 4olm coloured by chain, side view.
PDB entry 4olm coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Androgen receptor and peptide
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 11085.95 Å2
Buried surface area: 1697.02 Å2
Dissociation area: 435.99 Å2
Dissociation energy (ΔGdiss): 4.91 kcal/mol
Dissociation entropy (TΔSdiss): 6.78 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-145242

Macromolecules

Androgen receptor
Chain: A
Length: 250 amino acids
Theoretical weight: 29.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10275 (Residues: 671-920; Coverage: 27%)
Gene names: AR, DHTR, NR3C4
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
CATH: Retinoid X Receptor
Androgen receptor in PDB entry 4olm, assembly 1, front view.
Androgen receptor in PDB entry 4olm, assembly 1, side view.
Androgen receptor in PDB entry 4olm, assembly 1, top view.
Molecule details ›

Search similar proteins

co-regulator peptide
Chain: B
Length: 12 amino acids
Theoretical weight: 1.44 KDa
Source organism: Homo sapiens
Expression system: Not provided
co-regulator peptide in PDB entry 4olm, assembly 1, front view.
co-regulator peptide in PDB entry 4olm, assembly 1, side view.
co-regulator peptide in PDB entry 4olm, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links