4ojb

X-ray diffraction
2Å resolution

Crystal structure of W741L-AR-LBD

Released:
Source organism: Homo sapiens
Entry authors: Liu JS, Hsu CL, Wu WG

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Androgen receptor Chain: A
Molecule details ›
Chain: A
Length: 250 amino acids
Theoretical weight: 29.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10275 (Residues: 671-920; Coverage: 27%)
Gene names: AR, DHTR, NR3C4
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P212121
Unit cell:
a: 55.796Å b: 66.397Å c: 70.467Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.189 0.247
Expression system: Escherichia coli