X-ray diffraction
3.5Å resolution

Crystal Structure of ICAM-5 D1-D4 ectodomain fragment, Space Group R3

Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Intercellular adhesion molecule 5 Chain: A
Molecule details ›
Chain: A
Length: 378 amino acids
Theoretical weight: 41.31 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
  • Canonical: Q9UMF0 (Residues: 32-409; Coverage: 42%)
Gene names: ICAM5, TLCN, TLN
Sequence domains: Intercellular adhesion molecule (ICAM), N-terminal domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: R3
Unit cell:
a: 228.56Å b: 228.56Å c: 69.98Å
α: 90° β: 90° γ: 120°
R R work R free
0.244 0.242 0.273
Expression system: Homo sapiens