PDBe 4of5

X-ray diffraction
2.8Å resolution

Refinement of RAGE-DNA complex in 3S59 without DNA

Released:
Source organism: Homo sapiens
Primary publication:
The specificity of DNA recognition by the RAGE receptor.
OpenAccess logo J. Exp. Med. 211 749-50 (2014)
PMID: 24778420

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Advanced glycosylation end product-specific receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 223 amino acids
Theoretical weight: 24.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15109 (Residues: 23-237; Coverage: 56%)
Gene names: AGER, RAGE
Sequence domains: CD80-like C2-set immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P61
Unit cell:
a: 79.121Å b: 79.121Å c: 224.045Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.22 0.235
Expression system: Escherichia coli