4ocy

X-ray diffraction
2.79Å resolution

Fab for methotrexate (unbound apo)

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab ADD058 Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 216 amino acids
Theoretical weight: 23.24 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins
If kappa light chain Chain: L
Molecule details ›
Chain: L
Length: 216 amino acids
Theoretical weight: 23.78 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: A2NHM3 (Residues: 1-216; Coverage: 99%)
Gene names: Igk-C, Igkc
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P213
Unit cell:
a: 144.369Å b: 144.369Å c: 144.369Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.206
Expression system: Homo sapiens