4o37

X-ray diffraction
1.4Å resolution

seminsynthetic RNase S1-15-3Pl-7/11

Released:
Source organism: Bos taurus
Entry authors: Genz M, Strater N

Function and Biology Details

Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 15 amino acids
Theoretical weight: 1.77 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P61823 (Residues: 27-41; Coverage: 12%)
Gene names: RNASE1, RNS1
Ribonuclease pancreatic Chain: B
Molecule details ›
Chain: B
Length: 104 amino acids
Theoretical weight: 11.56 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 47-150; Coverage: 84%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P3121
Unit cell:
a: 43.82Å b: 43.82Å c: 96.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.174 0.211
Expression system: Not provided