PDBe 4nyh

X-ray diffraction
1.2Å resolution

Orthorhombic crystal form of pir1 dual specificity phosphatase core

Released:
Source organism: Homo sapiens
Primary publication:
Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
OpenAccess logo Biochemistry 53 862-71 (2014)
PMID: 24447265

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA/RNP complex-1-interacting phosphatase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 182 amino acids
Theoretical weight: 21.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: O75319 (Residues: 76-252)
Gene names: DUSP11, PIR1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 51.026Å b: 62.723Å c: 178.773Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.141 0.137 0.17
Expression system: Escherichia coli