X-ray diffraction
2.3Å resolution

Crystal structure of human ENDOV

Source organism: Homo sapiens
Primary publication:
Structure of human endonuclease V as an inosine-specific ribonuclease.
Acta Crystallogr. D Biol. Crystallogr. 70 2286-94 (2014)
PMID: 25195743

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Endonuclease V Chain: A
Molecule details ›
Chain: A
Length: 250 amino acids
Theoretical weight: 27.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q8N8Q3 (Residues: 13-250; Coverage: 84%)
  • Best match: Q8N8Q3-4 (Residues: 1-44)
Gene name: ENDOV
Sequence domains: Endonuclease V
Structure domains: archaeoglobus fulgidus dsm 4304 superfamily

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: Nova high-flux-micro-focus sealed tube
Spacegroup: P212121
Unit cell:
a: 39.75Å b: 48.713Å c: 108.531Å
α: 90° β: 90° γ: 90°
R R work R free
0.213 0.21 0.268
Expression system: Escherichia coli