4nrk

X-ray diffraction
2.63Å resolution

Structure of hemagglutinin with F95Y mutation of influenza virus B/Lee/40 complex with LSTc

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Hemagglutinin HA1 chain Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 346 amino acids
Theoretical weight: 37.76 KDa
Source organism: Influenza B virus (B/Lee/1940)
Expression system: Homo sapiens
UniProt:
  • Canonical: P03460 (Residues: 16-361; Coverage: 61%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin HA2 chain Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 182 amino acids
Theoretical weight: 19.54 KDa
Source organism: Influenza B virus (B/Lee/1940)
Expression system: Homo sapiens
UniProt:
  • Canonical: P03460 (Residues: 362-537; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Unit cell:
a: 83.61Å b: 128.3Å c: 211.81Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.207 0.245
Expression system: Homo sapiens