X-ray diffraction
2.15Å resolution

Structure of coiled-coil domain

Source organism: Homo sapiens
Entry authors: Yang M, Li Y

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
E3 ubiquitin-protein ligase TRIM69 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 179 amino acids
Theoretical weight: 20.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q86WT6 (Residues: 143-321; Coverage: 36%)
  • Best match: Q86WT6-2 (Residues: 3-162)
Gene names: HSD-34, HSD34, RNF36, TRIM69

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 83.097Å b: 101.064Å c: 233.252Å
α: 90° β: 90° γ: 90°
R R work R free
0.218 0.216 0.25
Expression system: Escherichia coli