4np3

X-ray diffraction
1.61Å resolution

Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule

Released:
Source organism: Mus musculus
Entry authors: Liu LK, Finzel B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD44 antigen Chain: A
Molecule details ›
Chain: A
Length: 150 amino acids
Theoretical weight: 16.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P15379 (Residues: 23-171; Coverage: 20%)
Gene names: Cd44, Ly-24
Sequence domains: Extracellular link domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 31Å b: 82Å c: 32Å
α: 90° β: 118° γ: 90°
R-values:
R R work R free
0.18 0.177 0.225
Expression system: Escherichia coli BL21(DE3)