› 4nfo

X-ray diffraction
1.96Å resolution

Crystal Structure Analysis of the 16mer GCAGACUUAAGUCUGC

Released:
DOI: 10.2210/pdb4nfo/pdb
PDB entry 4nfo coloured by chain, front view.
PDB entry 4nfo coloured by chain, side view.
PDB entry 4nfo coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Click modification of RNA at adenosine: structure and reactivity of 7-ethynyl- and 7-triazolyl-8-aza-7-deazaadenosine in RNA.
Phelps KJ, Ibarra-Soza JM, Tran K, Fisher AJ, Beal PA
ACS Chem Biol 9 1780-7 (2014)
PMID: 24896732

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196839 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
GCAGACUUAAGUCUGC Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 16 nucleotides
Theoretical weight: 5.1 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand SPM 1 x SPM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 74.98Å b: 43.08Å c: 48.76Å
α: 90° β: 120.98° γ: 90°
R-values:
R R work R free
0.218 0.217 0.242
Expression system: Not provided

Quick links

Citations

3 review citations

Therapeutic siRNA: state of the art.
Hu et al. (2020)
2 more

2 mentions without citation

Recent Advances in the Synthesis of Glycoconjugates for Vaccine Development.
Colombo et al. (2018)
1 more