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Crystal structure of a putative transcriptional regulator from Saccharomonospora viridis in complex with N,N-dimethylmethanamine

X-ray diffraction
2.05Å resolution
PDB entry 4nel coloured by chain, front view.
PDB entry 4nel coloured by chain, side view.
PDB entry 4nel coloured by chain, top view.
Source organism: Saccharomonospora viridis DSM 43017
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Transcriptional regulator
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Multimeric state: homo dimer
Accessible surface area: 16819.02 Å2
Buried surface area: 3240.16 Å2
Dissociation area: 1,620.08 Å2
Dissociation energy (ΔGdiss): 10.5 kcal/mol
Dissociation entropy (TΔSdiss): 12.99 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-111722

Macromolecules

Transcriptional regulator
Chain: A
Length: 190 amino acids
Theoretical weight: 22.34 KDa
Source organism: Saccharomonospora viridis DSM 43017
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: C7MT25 (Residues: 95-284; Coverage: 66%)
Gene name: Svir_16270
Pfam:
InterPro:
CATH: Tetracycline Repressor, domain 2
Transcriptional regulator in PDB entry 4nel, assembly 1, front view.
Transcriptional regulator in PDB entry 4nel, assembly 1, side view.
Transcriptional regulator in PDB entry 4nel, assembly 1, top view.
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