PDBe 4mbb

X-ray diffraction
1.85Å resolution

Cubic crystal form of PIR1 dual specificity phosphatase core

Released:
Source organism: Homo sapiens
Primary publication:
Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
OpenAccess logo Biochemistry 53 862-71 (2014)
PMID: 24447265

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA/RNP complex-1-interacting phosphatase Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 21.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: O75319 (Residues: 76-254)
Gene names: DUSP11, PIR1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P213
Unit cell:
a: 92.74Å b: 92.74Å c: 92.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.168 0.188
Expression system: Escherichia coli BL21(DE3)