› › Function and Biology

Crystal structure of purine nucleoside phosphorylase from Meiothermus ruber DSM 1279 complexed with sulfate.

Source organism: Meiothermus ruber DSM 1279
Biochemical function: pentosyltransferase activity
Biological process: nucleoside catabolic process
Cellular component: cytosol

Quick links

EC 2.4.2.3: Uridine phosphorylase

Reaction catalysed:
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate
Systematic name:
Uridine:phosphate alpha-D-ribosyltransferase
Alternative Name(s):
  • Pyrimidine phosphorylase
  • UPH
  • UPase
  • UrdPase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01048
Domain description: Phosphorylase superfamily
Occurring in:
  1. Uridine phosphorylase
The deposited structure of PDB entry 4mar contains 3 copies of Pfam domain PF01048 (Phosphorylase superfamily) in Uridine phosphorylase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR035994
Domain description: Nucleoside phosphorylase superfamily
Occurring in:
  1. Uridine phosphorylase
IPR004402
Domain description: Purine nucleoside phosphorylase DeoD-type
Occurring in:
  1. Uridine phosphorylase
IPR018016
Domain description: Nucleoside phosphorylase, conserved site
Occurring in:
  1. Uridine phosphorylase
IPR000845
Domain description: Nucleoside phosphorylase domain
Occurring in:
  1. Uridine phosphorylase

Structure domain

CATH CATH domain
3.40.50.1580
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Nucleoside phosphorylase domain
Occurring in:
  1. Uridine phosphorylase
The deposited structure of PDB entry 4mar contains 3 copies of CATH domain 3.40.50.1580 (Rossmann fold) in Uridine phosphorylase. Showing 1 copy in chain A.

Quick links