4m9p

X-ray diffraction
1.72Å resolution

Crystal structure of the human filamin A Ig-like domains 3-5

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Filamin-A Chain: A
Molecule details ›
Chain: A
Length: 291 amino acids
Theoretical weight: 31.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P21333 (Residues: 478-766; Coverage: 11%)
Gene names: FLN, FLN1, FLNA
Sequence domains: Filamin/ABP280 repeat
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P65
Unit cell:
a: 63.041Å b: 63.041Å c: 136.604Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.199 0.243
Expression system: Escherichia coli BL21