PDBe 4m5s

X-ray diffraction
1.37Å resolution

Human alphaB crystallin core domain in complex with C-terminal peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-crystallin B chain Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 9.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P02511 (Residues: 68-153; Coverage: 49%)
Gene names: CRYA2, CRYAB, HSPB5
Structure domains: Immunoglobulin-like
Alpha-crystallin B chain Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P02511 (Residues: 156-164; Coverage: 5%)
Gene names: CRYA2, CRYAB, HSPB5

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: I222
Unit cell:
a: 35.38Å b: 47.86Å c: 122.84Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.156 0.187
Expression system: Escherichia coli BL21(DE3)