4lud

X-ray diffraction
2.85Å resolution

Crystal Structure of HCK in complex with the fluorescent compound SKF86002

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase HCK Chains: A, B
Molecule details ›
Chains: A, B
Length: 454 amino acids
Theoretical weight: 52 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P08631 (Residues: 81-526; Coverage: 85%)
Gene name: HCK
Structure domains:

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21
Unit cell:
a: 48.3Å b: 73.4Å c: 180.29Å
α: 90° β: 96.77° γ: 90°
R-values:
R R work R free
0.215 0.212 0.261
Expression system: Spodoptera frugiperda