4llo

X-ray diffraction
2Å resolution

Structure of the eag domain-CNBHD complex of the mouse EAG1 channel

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Potassium voltage-gated channel subfamily H member 1 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 177 amino acids
Theoretical weight: 20.13 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60603 (Residues: 552-724; Coverage: 18%)
Gene names: Eag, Kcnh1
Sequence domains: Cyclic nucleotide-binding domain
Structure domains: Jelly Rolls
Potassium voltage-gated channel subfamily H member 1 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 134 amino acids
Theoretical weight: 15.52 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60603 (Residues: 6-136; Coverage: 13%)
Gene names: Eag, Kcnh1
Sequence domains: PAS domain
Structure domains: PAS domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P65
Unit cell:
a: 162.38Å b: 162.38Å c: 100.44Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.197
Expression system: Escherichia coli BL21(DE3)