PDBe 4lli

X-ray diffraction
2.2Å resolution

Crystal Structure of human Myosin 5a globular domain


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Unconventional myosin-Va Chains: A, B
Molecule details ›
Chains: A, B
Length: 395 amino acids
Theoretical weight: 45.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9Y4I1 (Residues: 1467-1855; Coverage: 21%)
Gene names: MYH12, MYO5A
Sequence domains: DIL domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 74.057Å b: 87.105Å c: 130.933Å
α: 90° β: 90° γ: 90°
R R work R free
0.201 0.198 0.246
Expression system: Escherichia coli BL21(DE3)