4lb7

X-ray diffraction
1.9Å resolution

Crystal structure of human alpha-defensin 1 (HNP1) Y16A/I20A/L25A/F28A mutant.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil defensin 1 Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 30 amino acids
Theoretical weight: 3.2 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P59665 (Residues: 65-94; Coverage: 40%)
Gene names: DEF1, DEFA1, DEFA1B, DEFA2, MRS
Sequence domains: Mammalian defensin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: R3
Unit cell:
a: 83.771Å b: 83.771Å c: 51.288Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.2 0.236
Expression system: Not provided