PDBe 4l3l

X-ray diffraction
2.1Å resolution

Crystal structures of human p70S6K1 kinase domain (Zinc anomalous)

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosomal protein S6 kinase beta-1 Chain: A
Molecule details ›
Chain: A
Length: 304 amino acids
Theoretical weight: 34.34 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P23443 (Residues: 75-375; Coverage: 57%)
Gene names: RPS6KB1, STK14A
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P41212
Unit cell:
a: 69.408Å b: 69.408Å c: 143.378Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.247
Expression system: Spodoptera frugiperda