PDBe 4kpr

X-ray diffraction
2.4Å resolution

Tetrameric form of rat selenoprotein thioredoxin reductase 1

Released:
Source organism: Rattus norvegicus
Entry authors: Lindqvist Y, Sandalova T, Xu J, Arner E

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin reductase 1, cytoplasmic Chains: A, B, E, F
Molecule details ›
Chains: A, B, E, F
Length: 499 amino acids
Theoretical weight: 54.77 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: O89049 (Residues: 1-499)
Gene names: Trxr1, Txnrd1

Ligands and Environments


Cofactor: Ligand FAD 4 x FAD
2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P3121
Unit cell:
a: 162.99Å b: 162.99Å c: 236.44Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.162 0.16 0.187
Expression system: Escherichia coli BL21(DE3)