X-ray diffraction
2Å resolution

A Cryptic TOG Domain with a Distinct Architecture Underlies CLASP-Dependent Bipolar Spindle Formation


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
CLIP-associating protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 273 amino acids
Theoretical weight: 30.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q7Z460 (Residues: 284-552; Coverage: 18%)
Gene names: CLASP1, KIAA0622, MAST1
Sequence domains: CLASP N terminal
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 62.284Å b: 66.492Å c: 138.934Å
α: 90° β: 90° γ: 90°
R R work R free
0.185 0.183 0.21
Expression system: Escherichia coli BL21(DE3)