4ju5

X-ray diffraction
2.28Å resolution

Crystal structure of the dimeric form of the bb' domains of human protein disulfide isomerase

Released:

Function and Biology Details

Reaction catalysed:
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein disulfide-isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 238 amino acids
Theoretical weight: 26.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P07237 (Residues: 135-367; Coverage: 48%)
Gene names: ERBA2L, P4HB, PDI, PDIA1, PO4DB
Sequence domains: Thioredoxin-like domain
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P1
Unit cell:
a: 40.521Å b: 45.718Å c: 55.149Å
α: 81.85° β: 92.15° γ: 80.02°
R-values:
R R work R free
0.245 0.243 0.29
Expression system: Escherichia coli BL21