4joi

X-ray diffraction
2.05Å resolution

Crystal structure of the human telomeric Stn1-Ten1 complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CST complex subunit STN1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 166 amino acids
Theoretical weight: 19.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H668 (Residues: 19-184; Coverage: 45%)
Gene names: OBFC1, STN1
Sequence domains: OB-fold nucleic acid binding domain
Structure domains: Nucleic acid-binding proteins
CST complex subunit TEN1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 122 amino acids
Theoretical weight: 13.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86WV5 (Residues: 2-123; Coverage: 99%)
Gene names: C17orf106, TEN1
Sequence domains: Telomere-capping, CST complex subunit
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P21212
Unit cell:
a: 130.613Å b: 58.101Å c: 87.458Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.211 0.249
Expression system: Escherichia coli