4jn1

X-ray diffraction
1.89Å resolution

An Antidote for Dabigatran

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
anti-dabigatran Fab1, heavy chain Chain: H
Molecule details ›
Chain: H
Length: 225 amino acids
Theoretical weight: 23.77 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
anti-dabigatran Fab1, light chain Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.07 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 113.132Å b: 78.217Å c: 63.434Å
α: 90° β: 89.91° γ: 90°
R-values:
R R work R free
0.177 0.176 0.197
Expression system: Not provided