4jan

X-ray diffraction
3.15Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Glycoprotein 120 Chains: G, I
Molecule details ›
Chains: G, I
Length: 355 amino acids
Theoretical weight: 39.27 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: R4GRV3 (Residues: 1-355; Coverage: 100%)
Sequence domains: Envelope glycoprotein GP120
ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103 Chains: A, H
Molecule details ›
Chains: A, H
Length: 226 amino acids
Theoretical weight: 23.9 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103 Chains: B, L
Molecule details ›
Chains: B, L
Length: 209 amino acids
Theoretical weight: 22.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 48.943Å b: 208.651Å c: 69.422Å
α: 90° β: 107.21° γ: 90°
R-values:
R R work R free
0.199 0.196 0.256
Expression system: Homo sapiens