X-ray diffraction
2.3Å resolution

Structure of designed HisF


Function and Biology Details

Reaction catalysed:
(1a) L-glutamine + H(2)O = L-glutamate + NH(3)
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Imidazole glycerol phosphate synthase subunit HisF Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 26.33 KDa
Source organism: Thermotoga maritima MSB8
Expression system: Escherichia coli
  • Canonical: Q9X0C6 (Residues: 97-220; Coverage: 85%)
Gene names: TM_1036, hisF
Structure domains: Aldolase class I

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 35.212Å b: 63.142Å c: 56.26Å
α: 90° β: 99.03° γ: 90°
R R work R free
0.244 0.242 0.297
Expression system: Escherichia coli