4j82

X-ray diffraction
1.46Å resolution

Crystal structure of beta'-COP/Insig-2 complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Coatomer subunit beta' Chains: A, B
Molecule details ›
Chains: A, B
Length: 301 amino acids
Theoretical weight: 34.29 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P41811 (Residues: 1-301; Coverage: 34%)
Gene names: G2827, SEC27, YGL137W
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Insulin-induced gene 2 protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 5 amino acids
Theoretical weight: 630 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9Y5U4 (Residues: 221-225; Coverage: 2%)
Gene name: INSIG2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P1
Unit cell:
a: 49.056Å b: 48.894Å c: 76.027Å
α: 88.83° β: 89.15° γ: 62.91°
R-values:
R R work R free
0.17 0.169 0.212
Expression system: Not provided