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Crystal structure of IFIT5/ISG58

Source organism: Homo sapiens
Biochemical function: poly(U) RNA binding
Biological process: response to other organism
Cellular component: apical part of cell

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF13374
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Interferon-induced protein with tetratricopeptide repeats 5
The deposited structure of PDB entry 4j0u contains 1 copy of Pfam domain PF13374 (Tetratricopeptide repeat) in Interferon-induced protein with tetratricopeptide repeats 5. Showing 1 copy in chain A.

PF13181
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Interferon-induced protein with tetratricopeptide repeats 5
The deposited structure of PDB entry 4j0u contains 1 copy of Pfam domain PF13181 (Tetratricopeptide repeat) in Interferon-induced protein with tetratricopeptide repeats 5. Showing 1 copy in chain A.

PF13424
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Interferon-induced protein with tetratricopeptide repeats 5
The deposited structure of PDB entry 4j0u contains 1 copy of Pfam domain PF13424 (Tetratricopeptide repeat) in Interferon-induced protein with tetratricopeptide repeats 5. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR019734
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Interferon-induced protein with tetratricopeptide repeats 5
IPR011990
Domain description: Tetratricopeptide-like helical domain superfamily
Occurring in:
  1. Interferon-induced protein with tetratricopeptide repeats 5
IPR013105
Domain description: Tetratricopeptide repeat 2
Occurring in:
  1. Interferon-induced protein with tetratricopeptide repeats 5

Structure domain

CATH CATH domain
1.25.40.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Tetratricopeptide repeat domain
Occurring in:
  1. Interferon-induced protein with tetratricopeptide repeats 5
The deposited structure of PDB entry 4j0u contains 2 copies of CATH domain 1.25.40.10 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Interferon-induced protein with tetratricopeptide repeats 5. Showing 2 copies in chain A.

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