› 4iye

X-ray diffraction
1.95Å resolution

Crystal structure of AdTx1 (rho-Da1a) from eastern green mamba (Dendroaspis angusticeps)

Released:
DOI: 10.2210/pdb4iye/pdb
PDB entry 4iye coloured by chain, front view.
PDB entry 4iye coloured by chain, side view.
PDB entry 4iye coloured by chain, top view.
Source organism: Dendroaspis angusticeps
Primary publication:
Crystallization of recombinant green mamba ρ-Da1a toxin during a lyophilization procedure and its structure determination.
Maïga A, Vera L, Marchetti C, Lorphelin A, Bellanger L, Mourier G, Servent D, Gilles N, Stura EA
Acta Crystallogr Sect F Struct Biol Cryst Commun 69 704-9 (2013)
PMID: 23722859

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160937 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxin AdTx1 Chain: A
Molecule details ›
Chain: A
Length: 66 amino acids
Theoretical weight: 7.3 KDa
Source organism: Dendroaspis angusticeps
Expression system: Escherichia coli
UniProt:
  • Canonical: P85092 (Residues: 1-65; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

2 bound ligands:
Ligand EDO 1 x EDO
Ligand PEG 2 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P3121
Unit cell:
a: 37.37Å b: 37.37Å c: 66.05Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.17 0.252
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural and Functional Diversity of Animal Toxins Interacting With GPCRs.
Van Baelen et al. (2022)
1 other article

4 mentions without citation

A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom.
Ramos et al. (2016)
3 more