PDBe 4irg

X-ray diffraction
1.7Å resolution

Uninhibited DNA-binding domain of the Ets transcription factor ERG

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional regulator ERG Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11308 (Residues: 313-412; Coverage: 21%)
Gene name: ERG
Sequence domains: Ets-domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P6522
Unit cell:
a: 44.699Å b: 44.699Å c: 175.112Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.188 0.228
Expression system: Escherichia coli