4im0

X-ray diffraction
2.4Å resolution

Structure of Tank-Binding Kinase 1

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase TBK1 Chain: A
Molecule details ›
Chain: A
Length: 663 amino acids
Theoretical weight: 76.19 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UHD2 (Residues: 1-657; Coverage: 90%)
Gene names: NAK, TBK1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P3221
Unit cell:
a: 133.921Å b: 133.921Å c: 85.67Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.199 0.236
Expression system: Spodoptera frugiperda