X-ray diffraction
2.05Å resolution

Crystal Structure of a Gly128Met mutant of the toxoplasma CDPK, TGME49_101440

Source organism: Toxoplasma gondii
Entry authors: Wernimont AK, Artz JD, El Bakkouri M, Schapira M, Edwards AM, Arrowsmith CH, Bountra C, Hui R, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Calmodulin-domain protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 515 amino acids
Theoretical weight: 58.48 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
  • Canonical: Q9BJF5 (Residues: 1-507; Coverage: 100%)
Gene name: CDPK1
Sequence domains: EF-hand domain pair
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 50.174Å b: 96.684Å c: 102.36Å
α: 90° β: 90° γ: 90°
R R work R free
0.176 0.174 0.217
Expression system: Escherichia coli