› 4icn

X-ray diffraction
2.5Å resolution

Dihydrodipicolinate synthase from shewanella benthica

Released:
DOI: 10.2210/pdb4icn/pdb
PDB entry 4icn coloured by chain, front view.
PDB entry 4icn coloured by chain, side view.
PDB entry 4icn coloured by chain, top view.
Source organism: Shewanella benthica
Entry authors: Wubben JM, Paxman JJ, Dogovski C, Parker MW, Perugini MA

Function and Biology Details

Reaction catalysed: 
Pyruvate + L-aspartate-4-semialdehyde = (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108975 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
4-hydroxy-tetrahydrodipicolinate synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 300 amino acids
Theoretical weight: 31.63 KDa
Source organism: Shewanella benthica
Expression system: Escherichia coli
UniProt:
  • Canonical: A9DKW4 (Residues: 11-310; Coverage: 97%)
Gene names: KT99_11964, dapA
Sequence domains: Dihydrodipicolinate synthetase family
Structure domains: Aldolase class I

Ligands and Environments

4 bound ligands:
Ligand TRS 1 x TRS
Ligand GOL 3 x GOL
Ligand SO4 2 x SO4
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 73.09Å b: 84.03Å c: 143.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.199 0.25
Expression system: Escherichia coli

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