4iar

X-ray diffraction
2.7Å resolution

Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-hydroxytryptamine receptor 1B; Soluble cytochrome b562 Chain: A
Molecule details ›
Chain: A
Length: 401 amino acids
Theoretical weight: 45.27 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P28222 (Residues: 33-239, 306-390; Coverage: 75%)
  • Canonical: P0ABE7 (Residues: 23-128; Coverage: 100%)
Gene names: HTR1B, HTR1DB, cybC
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D, APS BEAMLINE 21-ID-D
Spacegroup: C2
Unit cell:
a: 195.29Å b: 45.5Å c: 74.28Å
α: 90° β: 95.45° γ: 90°
R-values:
R R work R free
0.225 0.223 0.261
Expression system: Spodoptera frugiperda