4i29

X-ray diffraction
2.2Å resolution

Binary complex of mouse TdT with ssDNA and Mn++

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
DNA nucleotidylexotransferase Chain: A
Molecule details ›
Chain: A
Length: 400 amino acids
Theoretical weight: 45.7 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P09838 (Residues: 132-510; Coverage: 74%)
Gene names: Dntt, Tdt
Sequence domains:
Structure domains:
5'-D(*AP*AP*(8BA)P*AP*A)-3' Chain: C
Molecule details ›
Chain: C
Length: 5 nucleotides
Theoretical weight: 1.6 KDa
Source organism: Mus musculus
Expression system: Not provided

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 46.755Å b: 84.923Å c: 115.141Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.177 0.225
Expression systems:
  • Escherichia coli
  • Not provided